Shape-Controlled Nanoparticles from a Low-Energy Nanoemulsion

Nanoemulsion technology enables the production of uniform nanoparticles for a wide range of applications. However, existing nanoemulsion strategies are limited to the production of spherical nanoparticles. In our latest work, the group of Polymeric Materials in collaboration with the group of Soft and Living Materials, developed a low-energy nanoemulsion method to produce nanoparticles with various morphologies. By selecting a macroRAFT agent (poly(di(ethylene glycol) ethyl ether methacrylate-co-N-(2- hydroxypropyl) methacrylamide) (P(DEGMA-co-HPMA))) that dramatically lowers the interfacial tension between monomer droplets and water, we can easily produce nanoemulsions at room temperature by manual shaking for a few seconds. With the addition of a common ionic surfactant (SDS), these nanoscale droplets are robustly stabilized at both the formation and elevated temperatures. Upon polymerization, we produce well-defined block copolymers forming nanoparticles with a wide range of controlled morphologies, including spheres, worm balls, worms, and vesicles. Our nanoemulsion polymerization is robust and well-controlled even without stirring or external deoxygenation.