Dr. Matthias Le Bec
Dr. Matthias Le Bec
Staff of Professorship for Soft Materials and Interfaces
ETH Zürich
Additional information
Research area
I am working as postdoctoral researcher in Prof. Lucio Isa's team on the use of microfluidic bacterial spore deposition to study active nematic systems. The project aims to control the initial spore spatial configuration to shape predictable bacteria growth patterns.
Main research fields: Biophysics, Microbiology, Synthetic biology, Biochemistry, Microfluidics.
Education
2019-2022 PhD – Université Paris Cité & Institut Curie (UMR 168), France
2017-2018 Double diploma M.Sc. “Chemical Frontiers of Living Matter” - University PSL, France
2015-2018 “Diplome d'ingénieur” (M.Sc. equivalent) - Chimie ParisTech, France
2013-2015 Preparatory class BCPST (Bachelor equivalent) - Lycée Louis Barthou, France
Previous research experience
2019-2022 PhD student - “Spatiotemporal control of cooperation in yeast communities”, Supervisor: Dr. Pascal Hersen, Physical Chemistry Curie Unit (UMR 168) Paris, France.
2018-2019 Research engineer - Université Paris Cité, Matière et Systèmes Complexes lab, Pascal Hersen’s team, France.
2018 Master 2 intern (6 months) – L. Jullien’s team, Biophysics and chemistry, ENS Paris, France.
2017 Master 1 intern (5 months) – C. Doherty’s team, CSIRO Melbourne, Australia.
Publications
1. Optogenetic spatial patterning of cooperation in yeast populations - M. Le Bec, S. Pouzet, C. Cordier, S. Barral, V. Scolari, B. Sorre, A. Banderas, P. Hersen – Nature Communications 15, 75 (2024).
2. Spatiotemporal control of cooperation in yeast communities – M. Le Bec – PhD thesis, Université Paris Cité (2022).
3. Cybersco.py: software for event-based, conditional microscopy - M. Le Bec, L. Chiron, C. Cordier, S. Pouzet, D. Milunov, A. Banderas, J. Di Meglio, B. Sorre, P. Hersen - Scientific Reports 12, 11579 (2022).
4. Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales – S. Pouzet, J. Cruz-Ramon, M. Le Bec, C. Cordier, A. Banderas, S. Barral, S. Castano-Cerezo, T. Lautier, G. Truan and P. Hersen - Frontiers in Bioengineering and Biotechnology 11, (2023).
5. Autonomous and assisted control for synthetic microbiology – A. Banderas, M. Le Bec, C. Cordier, P. Hersen - International Journal of Molecular Sciences 21 (23), 9223 (2020).
6. The promise of optogenetics for bioproduction: dynamic control strategies and scale-up instruments – S. Pouzet, A. Banderas, M. Le Bec, T. Lautier, G. Truan, P. Hersen - Bioengineering 7 (4), 151 (2020).